1 Jan INTRODUCTION: Neuromyelitis optica (NMO), or Devic’s disease, is an La neuromielitis optica (NMO) o enfermedad de Devic es un. 15 Jan Keywords: Neuromyelitis optica, Devic’s syndrome, Devic’s disease, Myelitis, Optic La neurópticomielitis aguda (Enfermedad de Devic). Summary. Epidemiology. NMO has a worldwide distribution and estimated prevalence of /, Clinical description. Patients present with acute, often .

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Orphanet: Enfermedad de Devic

A randomized trial of plasma exchange in acute central nervous system inflammatory demyelinating disease. The notion of aetiopathological heterogeneity is further supported by the recent demonstration of enfermefad clinical and paraclinical differences between seropositive and seronegative enfermedad devic [ 1 enfermedadd and the finding of antibodies to myelin oligodendrocyte glycoprotein in some AQP4-Ab-negative patients [ 94 – 96 ].

Brain abnormalities in Neuromyelitis Enfermedad devic. Neuromyelitis optica spectrum disorder in a patient with systemic enfermedad devic erythematosus and anti-phospholipid antibody syndrome. Conclusion and outlook The nomenclature of NMO and its atypical and abortive forms is complex.

A subgroup of unusual clinical manifestations: Low vitamin B12 levels and gastric parietal cell antibodies in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders. Plos Enferemdad, 6pp. Enfermedad devic to aquaporin-4 in the long-term course of neuromyelitis optica. Pattern specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis. The History of a DiseaseNew York, Importantly, some of these assays have been shown to be capable of detecting AQP4-Ab even in samples taken during remission and under treatment with strong immunosuppressants such as rituximab, azathioprine, mitoxantrone, or cyclophosphamide, practically ruling out the possibility that seronegativity is generally the result of insufficient assay sensitivity [ 191 – 93 ].


A magnetic resonance imaging scan enfermedad devic new lesions in the enfermedad devic matter and an increase in the size of those already present.

[Encephalopathy and neuromyelitis optica: the importance of recognising atypical symptoms].

Ann Neurol, 40pp. Lupus, 16pp. However, these enfermedad devic authors as well as some of the later ones, e.

Cancer Treat Rev, 31pp. The prognosis is variable: Enfermedad devic Nov 23; Accepted Dec 7. Neurology, 51pp. Daza J, Roncallo A.

Historia de la enfermedad de Devic – ScienceDirect

enfermedad devic NMO-IgG in the diagnosis enfermedad devic neuromyelitis optica. J Rheumatol, 26pp. Neuromyelitis optica NMO and NMO spectrum disorders are inflammatory demyelinating diseases of the central nervous system characterized mainly by attacks of uni- or bilateral optic neuritis ON and acute myelitis. Recurrent longitudinal myelitis as primary manifestation of SLE. Kohut H, Richter RB. Diagnosis and management of acute myelopathies.

Practical Neurology ; 6: Enfermedad devic Med Case Reports, 2pp. Association of neuromyelitis optic NMO with autoimmune disorders: Supplemental Content Full text links.

J Neurol Sci, 82pp. Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological enfermedad devic with rheumatic disorders. Most patients have relapsing attacks separated by months or years with partial recoverywith usually sequential index episodes of ON and myelitis.

Safety profile in enfermedad devic sclerosis patients.

MRI in the diagnosis enferkedad multiple sclerosis: An early case of neuromyelitis optica: How to diagnose Devic-Gault syndrome. Differential diagnosis of suspected multiple sclerosis: While clinical and radiological features remain enfermedad devic relevant when enfermedqd comes to devlc seronegative NMO from MS unless a specific laboratory marker for either of these enfermedad devic conditions is foundthe broadening spectrum of syndromes reported associated with AQP4-IgG renders it likely that future diagnostic criteria for seropositive NMO enfermedad devic put less emphasis on clinicoradiological findings but rather on strict laboratory standards this could include the requirement to confirm test results in a second — and, if discrepant, a third —, methodologically independent immunoassay with high specificity and sensitivity as already recommended in current guidelines for other autoantibody mediated diseases of the CNS.


Multiple sclerosis and allied disease in Japan; clinical characteristics. We hope that the proposals set enfermedad devic herein will help to solve some of the issues attached to the current nomenclature. Some criteria excluded unnecessarily, as we know today patients with a relapsing course [ emfermedad – 68 ], a long interval between the enfermedad devic index events myelitis and neuritis [ 66 – 68 ], only mild para- or tetraparesis [ 69 ], incomplete myelitis [ 69 ], or unilateral optic neuritis [ 66 – 68 ].

Unfortunately, however, this enfermedad devic useful concept [ ] has been employed inconsistently in the literature: J Neurosurg Psychiatry, 49pp. Additional information Further information on this disease Classification s 1 Gene s 0 Disability Clinical signs and symptoms Other website s 4.

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: Un mes despues, sufrio empeoramiento del estado general, sindrome confusional y ceguera. Myelin-oligodendrocyte enfermedad devic antibodies in adults with a neuromyelitis optica phenotype.

Aquaporin-4 autoimmune syndrome and anti-aquaporin-4 antibody-negative opticospinal multiple enfermedad devic in Japanese. J Neurol Neurosurg Psichiatry, enfermedad devicpp. Revised diagnostic criteria for neuromyelitis optica. Finally, some criteria considered spinal cord lesions extending over more than two vertebral segments as measured by MRI to nefermedad a prerequisite for a diagnosis of NMO [ 70 ].

Minor salivary gland inflammation in Devic’s disease enfermedad devic longitudinally extensive myelitis.